Construction of conductive hydroxyethyl cellulose/soy protein isolate/polypyrrole composite sponges and their performances

In the present study, we have in situ synthesized polypyrrole (PPy) on hydroxyethyl cellulose/soy protein isolate (HEC/SPI) sponges to construct electro-conductive HEC/SPI/PPy composite (EHSS-Pn, n > 0). The were characterized by Fourier transform infrared spectroscopy X-ray diffraction, scanning electron microscopy, conductivity and mechanical tests. results indicated that EHSS-Pn still exhibit homogenous inter-connected macroporous structure for cell adhesion, proliferation metabolism, indicating incorporation of PPy didn’t break original HEC/SPI sponge structure. electrical properties improved significantly PPy. Cytocompatibility hemocompatibility all evaluated a series vitro experiments. MTT assay direct contact tests showed introduction cause any cytotoxicity had good biocompatibility. Moreover, no obvious side effects as-prepared anticoagulant whole blood after Therefore, potential application tissue engineering field requires stimulation or sensing such as neural restoration.